Every discussion of CRISPR gene editing technology seems to come with an obligatory but superficial mention of the ethical dilemmas it brings up, especially in the context of applying it to the human germ line. Everyone asks questions like Should we remove sickle cell anemia from the gene pool? Where do we draw the line between curing diseases and building designer babies? What if everyone opts for 6-foot tall blonde-haired, blue-eyed archetype? Should we allow trans-human enhancements like taking genes from the mantis shrimp to give ourselves hyperspectral 16-color vision? What if only the rich have access, and become a ruling cadre of genetic elites, passing heritable enhancements down through their segregated bloodlines? Aren’t we playing God? How can we avoid becoming a society that looks like Gattaca or Brave New World? What thoughtful, proactive regulations can we enact to ensure this technology is used only for good, and that ethical boundaries are respected?
These questions are a fine starting point, but they also seem to be where popular explorations of this technological quandary end. I listened to Ezra Klein’s interview with Walter Isaacson on the topic this morning over coffee, and big chunks of it sounded like they could have been taken verbatim from the recent documentary Human Nature.
This hypothetical ethical discussion feels like it’s taking place in relation to a hypothetical society that makes well-reasoned policy decisions based on a shared idea of what’s right and good in the best long-term interests of society at large. A society that, having made those good decisions, can actually enforce them.
How can anybody think that’s the world we live in?Continue reading CRISPR Ethics in the Real World